I usually kick chests to unlock them (if I dont have the key). I recently came across one that wouldnt open when I kicked it so i picked it up and threw it against the wall. Voila!
then in the last game i played, first 3 steps into the dungeon I find sal thuul. nice. one of my favorite weapons in the game. i com across a chest 3 steps later and for some reason i decided to pick it up and throw it against the wall instead of kicking it. you hear something shatter. you are covered in sulphuric acid (and of course 2 turns later) you die. I have not seen that happen when i kick chests , have i just been lucky, or is throwing chest more dangerous?
unrelated point, i love when i find one of the hidden chests, and when i finally get it open one of the goodies inside is another chest, its like finding double the treasure.