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Use scroll of detect material to detect "enner beast flesh", teleport near him (not right next to him) and use FIREBALLS not striking. Striking does no good against him, fireballs usually takes 2, at most 3 shots.
Hmm, I once killed enner with a wand of striking, but that was on a bone level where he already got hurt before, IIRC. I also once got him killed, surprise surprise, by my agility-pumped mistresses.
(other than that, it's mostly luck for me, because I only got past enner a few times)
Ps. Does anyone know whether enner can be given leprosy by Scabies, or perhaps kicked around a bit by Silva's earthquakes? I've not much time to experiment right now.