Though many people may simply not mention them because of how simple they are and that they can be accessed simply by clicking the '?' button, I feel that all keys need to be mentioned because not having the knowledge about one important one can hurt a run a lot.  Also, you can view most if not all of them here: [[Commands]]. I just tried to put some details in mine. That said, let's go through the most important keys:

'''up, down, left, and right Arrow''': Self Explanatory, Movement keys. '''Home and End''' (Located in the top right corner of the keyboard), '''Page Up and Page Down''' (Located in the bottom right corner of the keyboard): Not so self explanatory. These keys, which aren't mentioned for whatever reason, allow you to move diagonally. Homes moves you up and left, End moves you down and left, Page Up is up and right, and Page Down is down and right. Importantly, it's counted as a single move. Even more importantly, it allows you to interact with otherwise non-interactable objects, most notably being 2 of [[Haathbar]]'s bookshelf. '''MOST IMPORTANTLY''', and I cannot stress this enough because it makes your run so much safer, being at a diagonal greatly decreases damage from certain entities, including trapped door explosions, zaps from [[Wand of Fireballs]] and [[Wand of Lightning]], and the [[Enner Beast]] scream.